There is some evidence that obese individuals do have a shortage of lipase. Researchers at Tufts University School of Medicine conducted some tests on the abdominal fat of 11 extra heavy individuals (average of 340 pounds) and found a lipase enzyme deficiency in their fat cells.

This could be explained by the fact that obesity and abnormal cholesterol deposits both have their beginnings in our failure to permit fat pre-digestion of cooked or processed foods in the upper stomach due to the fact that the natural lipase content of fatty foods has been destroyed by cooking.

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